pyridone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4805	α-Pyridone	2-Hydroxypyridine	Others , Endogenous Metabolite
	α-Pyridone (2-Hydroxypyridine)e is the catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.		Others , Endogenous Metabolite
T3080	Pyridone 6	Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I	Tyrosine Kinases , JAK
	Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM...		Tyrosine Kinases , JAK
T2253	TCS PIM-1 1	SC 204330	Pim
	TCS PIM-1 1 (SC 204330)(sc-204330) is a effective and specific ATP-competitive Pim-1 kianse inhibitor (IC50: 50 nM) , exhibits good specific over MEK1/MEK2 and Pim-2(IC50s >20, 000 nM).		Pim
T13146	Thienopyridone		Others
	Thienopyridone is a potent and selective inhibitor of phosphatase of regenerating liver (PRL) phosphatase(IC50s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3, respectively), and induces p130Cas cleavage and ap...		Others
TN6092	Aspyridone A
	Aspyridone A is a natural product for research related to life sciences. The catalog number is TN6092 and the CAS number is 935863-26-6.
T60774	NITD-916	NITD916,NITD 916	Antibiotic
	NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NA...		Antibiotic
T71459	PD 163449
	PD 163449 is a bioactive molecule of 4-pyridone group that inhibits bacterial type IIA topoisomerase (DNA gyrase and topoisomerase IV).
T34310	RG 14921	RG14921,RG-14921
	RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.
T75455	Paecilomide
	Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .
T29527	ABT-255	ABT 255,ABT255,UNII-YA04O24J4T
	ABT-255 is a novel 2-pyridone antimicrobial agent for the treatment of tuberculosis. Both drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis showed efficacy in vitro and in vivo.
T64138	Cap-dependent endonuclease-IN-16
	Cap-dependent endonuclease-IN-16 is a pyridone polycyclic derivative and a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-16 shows potential for influenza studies.
T38230	Iromycin A
	Iromycin A is a bacterial pyridone metabolite that inhibits nitric oxide synthase (NOS) activity, with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS). Iromycin metabolites and derivatives block NADH ...
T83090	Anticancer agent 131
	HCT-116-IN-1, a γ-lactam-fused pyridone derivative, exhibits anticancer properties, demonstrating significant cytotoxicity towards HCT116 cells, with an IC50 value of 5.59 μM [1].