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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6357 | (S)-crizotinib | ent-crizotinib | Apoptosis , DNA/RNA Synthesis , MTH1 |
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib. | |||
T2S1635 | 3-Isomangostin | MTH1 | |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac... | |||
T12122 | MTH1-IN-2 | MTH1 | |
MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity. | |||
T83818 | Isoguanosine-5'-O-triphosphate sodium | 2-Hydroxyadenosine 5’-triphosphate,2-hydroxy ATP,isoGTP | |
Isoguanosine-5'-O-triphosphate, an isomer of guanosine 5'-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcri... |