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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21351 | Maytansine | NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine | Microtubule Associated , Antibiotic |
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. | |||
T36647 | Trastuzumab emtansine | Others | |
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that combines the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of DM1, a microtubule-inhibitory deriv... | |||
T18278 | Mal-PEG2-VCP-Eribulin | Others | |
Mal-PEG2-VCP-Eribulin is a chemotherapeutic compound comprising an antibody-drug conjugate (ADC) linker (Mal-PEG2-VCP) and the microtubule inhibitor Eribulin[1]. This compound uniquely targets microtubules, offering a no... | |||
T68232 | Epofolate | ||
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th... | |||
T77186 | Zilovertamab vedotin | ||
Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate consisting of the humanized monoclonal antibody zilovertamab linked to the anti-microtubule cytotoxin monomethyl auristatin E (MMAE). Upon binding to ROR1... |