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Search Results for " melastatin "

9

Compounds

Cat No. Product Name Synonyms Targets
T16483 PF-05105679 TRP/TRPV Channel
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain.
T8442 M8-B Hydrochloride TRP/TRPV Channel
M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.
T10300 AMG2850 TRP/TRPV Channel
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
T22537 9-Phenanthrol TRP/TRPV Channel
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
T9776 TRPM4 inhibitor 8 TRP/TRPV Channel
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.
T17006 TC-I 2014 TRP/TRPV Channel
TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine,...
T78981 Xeniafaraunol A
Xeniafaraunol A (compound 31) is a potent inhibitor of the transient receptor potential melastatin 7 (TRPM7) channel [1].
T61275 TRPM4-IN-2 NBA TRP/TRPV Channel
TRPM4-IN-2 (NBA), also known as NBA, is a highly effective inhibitor of transient receptor potential melastatin 4 (TRPM4). Its inhibitory potency is represented by an IC 50 value of 0.16 μM. This compound serves as a val...
T83730 Tat-M2NX TFA
Tat-M2NX, a peptide antagonist of transient receptor potential melastatin 2 (TRPM2), blocks hydrogen peroxide-induced calcium influx in HEK293 cells expressing human TRPM2 at concentrations between 25 to 100 µM. In male ...
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