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Search Results for " midh1-in-1 "

2

Compounds

Cat No. Product Name Synonyms Targets
T62698 mIDH1-IN-1
mIDH1-IN-1 (compound 43) is a potent and selective inhibitor of mIDH1 (isocitrate dehydrogenase 1 mutant) (IC50: 961.5 nM). mIDH1-IN-1 effectively inhibits the production of 2-HG (2-hydroxyglutarate) in HT1080 cells (EC5...
T3617 Ivosidenib AG-120 Dehydrogenase , Isocitrate Dehydrogenase (IDH)
Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhi...
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