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Search Results for " machr-in-1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T5476 mAChr-in-1 AChR
mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).
T5655 mAChR-IN-1 hydrochloride AChR
mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.
T19870 Aceclidine 3-Acetoxyquinuclidine,1-azabicyclo[2.2.2]octan-3-yl acetate,NSC657843,3-quinuclidinyl acetate,NSC-657843,Glaucostat,NSC 657843,Quinuclidin-3-yl acetate AChR
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure.
T14345 Atropine methyl bromide Methylatropine bromide AChR
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic exa...
T60536 Terodiline
Terodiline is a Ca 2+ blocker and M1-selective muscarinic receptor (mAChR) antagonist with Kb of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodil...
T61878 N-Demethyl MK-6884
N-Demethyl MK-6884 (compound 34) is an influential allosteric modulator of the M4 mAChR, which finds applicability in Alzheimer's disease research as well as the study of other diseases influenced by the M4 mAChR [1].
T60577 Cycrimine
Cycrimine is an orally active antagonist of the muscarinic cholinergic receptor (mAChR) M1 that reduces the level of acetylcholine in the Parkinson's model. Cycrimine exhibits antispasmodic activity that can be used in b...
T74988 DIBA-Cy5
DIBA-Cy5, a fluorescent DIBA antagonist, consists of DIBA-alkyne and Cyanine5 fluorophores (Cy5) linked by a polyethylene glycol (PEG) chain. It functions as a fluorescent ligand for probe attachment via click chemistry,...
T73272 VU6019650
VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR ( IC 50 =36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopa...
TargetMol