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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3258 | Ponesimod | ACT-128800 | S1P Receptor , LPL Receptor |
Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity. | |||
T7981 | 2-Fluoroadenosine | Others | |
2-Fluoroadenosine is a potent inhibitor of lymphocyte-mediated cytolysis. | |||
T3626 | Acalabrutinib | ACP-196 | BTK |
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre... | |||
T28708 | Sch 24937 | ||
Sch 24937 is a potent immunosuppressant on B lymphocyte mediated immune responses. | |||
T37675 | 3-Deaza-2'-deoxyadenosine | ||
3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM. This nucleoside can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure an... | |||
T3977L | Lifitegrast sodium | SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra | |
Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte functio... | |||
T77188 | Tifcemalimab | ||
Tifcemalimab (JS004), a humanized monoclonal antibody targeting BTLA (B and T lymphocyte attenuation factor), inhibits the HVEM-BTLA interaction by binding to BTLA. This action prevents the BTLA-mediated inhibitory signa... | |||
T76241 | Trichomide A | ||
Trichomide A, a natural cyclodepsipeptide, serves as a potent activator of SHP2. This compound exhibits immunosuppressive activity against activated T lymphocyte-mediated immune responses in Con A-activated T cells, high... |