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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18363 | Monoethyl pimelate | Others , PROTAC Linker | |
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1]. | |||
T9382 | Thalidomide-NH-C2-PEG3-OH | H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]- | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate. | |||
T39701 | Pomalidomide-C7-COOH | Pomalidomide-C7-COOH | |
Pomalidomide-C7-COOH is a chemically synthesized E3 ligase cereblon ligand-linker conjugate, utilized as an intermediate compound for the synthesis of PROTAC BCL-XL degraders. | |||
T73957 | PROTAC Bcl-xL degrader-1 | ||
PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits to... | |||
T18671 | (S,R,S)-AHPC-Me-C7 ester | Others | |
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1]. | |||
T39604 | Thalidomide-NH-PEG4-Ms | Thalidomide-NH-PEG4-Ms | |
Thalidomide-NH-PEG4-Ms is a conjugate that consists of a cereblon ligand based on Thalidomide and a linker molecule, which serves as a ligand-linker moiety for E3 ligase. This conjugate is specifically designed as a degr... |