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Search Results for " isoxazoline "

6

Compounds

Cat No. Product Name Synonyms Targets
T16845 Sarolaner PF-6450567 Others , Parasite
Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).
T13536 Afoxolaner Chloride channel , GABA Receptor , Parasite
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting i...
T9858 5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole Parasite
Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.
T5330 Fluralaner AH252723,A1443 GABA Receptor , Parasite
Fluralaner (A1443) is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head membranes (IC50: 455 pM).
T11307 Fluxametamide GABA Receptor
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225...
T79762 Insecticidal agent 4
Compound IA-8, an aryl isoxazoline derivative, exhibits insecticidal efficacy against M. separate [1].
TargetMol