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Sarolaner

Catalog No. T16845 CAS 1398609-39-6

Synonyms: PF-6450567

Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Sarolaner, CAS 1398609-39-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 44.00
5 mg	In stock	$ 97.00
10 mg	In stock	$ 178.00
25 mg	In stock	$ 378.00
50 mg	In stock	$ 568.00
100 mg	In stock	$ 815.00
1 mL * 10 mM (in DMSO)	In stock	$ 135.00

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Purity: 99.88%

Purity: 99.65%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).
Targets&IC50	LC80: 0.3μg/ml(C. felis), LC100: 0.003 μg/ml(O. turicata)

Synonyms	PF-6450567
Molecular Weight	581.36
Formula	C23H18Cl2F4N2O5S
CAS No.	1398609-39-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 290 mg/mL (498.83 mM), Sonication is recommended.

References and Literature

1. McTier TL, et al. Discovery of sarolaner: A novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs. Vet Parasitol. 2016 May 30;222:3-11.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Parasitic Compound Library Anti-Infection Compound Library Orally Active Compound Library Bioactive Compounds Library Max Bioactive Compound Library

Related Products

Related compounds with same targets

trans-Clopenthixol dihydrochloride Albendazole 5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole Piperaquine Chloroquine AP-C5 Selamectin Robenidine hydrochloride

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sarolaner 1398609-39-6 Microbiology/Virology Others Parasite dog flea Inhibitor oral inhibit PF6450567 isoxazoline tick PF-6450567 PF 6450567 inhibitor

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