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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10466 | BAY-1797 | P2X Receptor | |
BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels. | |||
T2735 | 5-Acetylsalicylic acid | 5-acetyl-2-hydroxybenzoic acid | Others |
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ... | |||
T15360 | Furobufen | Others | |
Furobufen is an anti-inflammatory agent. It produces antiarthritic and has antipyretic effects. Furobufen also has an analgesic effect in inflamed tissue. | |||
T70616 | ACT-672125 | ||
ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672... | |||
T69830 | GSK2239633 | ||
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2... | |||
T60957 | Palmitoyl serinol | ||
Palmitoyl serinol (N-Palmitoyl serinol) is the endocannabinoid N-palmitoyl ethanolamine (PEA) analog that improves both normal and inflamed skin epidermal permeability barrier [1] [2]. | |||
T74975 | Zn-DPA-maytansinoid conjugate 1 | ||
Zn-DPA-maytansinoid conjugate 1, a small molecule-based immune checkpoint-targeting maytansinoid conjugate, effectively induces sustained tumor growth regression and transforms the tumor microenvironment (TME) into an "i... | |||
T37389 | NS 383 | ||
ASIC blocker (IC50 values are 0.44, 2.1 μM and no effect at rat ASIC1a, ASIC3 and ASIC2a, respectively: IC50 value = 0.12 μM at human ASIC1a with no effect at ASIC2a or ASIC3). Inhibition was also observed at heteromeric... | |||
T71288 | Phenylbutazone-d9 | ||
Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity... | |||
T37606 | Resolvin D5 | 7(S),17(S)-diHDHA | |
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid . [1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory respons... | |||
T35946 | 17(R)-Resolvin D1 | Aspirin-triggered Resolvin D1,17(R)-Resolvin D1 | |
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response ... |