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Search Results for " hyperphosphatemia "

4

Compounds

Cat No. Product Name Synonyms Targets
T7587 Tenapanor RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722 Sodium Channel
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinica...
T6344 Sevelamer hydrochloride Sevelamer HCl FXR , Autophagy
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
T70605 NaPi2b Inhibitor 15
NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to re...
T78146 NaPi2b-IN-2 Others
NaPi2b-IN-2 (compound 5) serves as a potent inhibitor of the sodium-dependent transport protein 2b (SLC34A2, NaPi2b), exhibiting an IC50 of 38 nM against human NaPi2b. It holds potential for use in hyperphosphatemia rese...
TargetMol