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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1563 | Gap19 | Gap Junction Protein | |
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43. | |||
TP2110L | TAT-Gap19 acetate | Gap Junction Protein | |
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the correspondi... | |||
TP2110 | TAT-Gap19 | ||
Cx43 hemichannel blocker (IC50 ~7 μM). No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of... | |||
T41204 | TAT-Gap19(I130A) | TAT-Gap19(I130A) | |
TAT-Gap19(I130A) is a control peptide for TAT-Gap19, a Cx43 hemichannel blocker. TAT-Gap19(I130A) consists of TAT-GAP19 with a I130A amino acid residue change at a key residue for GAP19 activity. In C6 glioma cells expre... | |||
T75821 | TAT-Gap19 TFA | ||
TAT-Gap19 TFA, a Cx mimetic peptide and specific connexin43 hemichannel (Cx43 HC) inhibitor, does not inhibit the corresponding Cx43 gap junction channels (GJCs). It crosses the blood-brain barrier and has been shown to ... | |||
T75820 | Gap19 TFA | ||
Gap19 TFA is a selective and potent blocker of connexin 43 (Cx43) hemichannels, originating from nine amino acids within the Cx43 cytoplasmic loop (CL). It operates by hindering intramolecular interactions between the C-... | |||
T83682 | Tat-Gap 19 TFA | ||
Tat-Gap 19, a peptide inhibitor of connexin43 (Cx43) hemichannels, is derived from the HIV-1 Tat protein transduction domain fused with a nine-amino acid sequence from Cx43 residues 128-136. This compound, at a concentra... |