Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 338.00 | |
25 mg | In stock | $ 597.00 | |
50 mg | In stock | $ 852.00 | |
100 mg | In stock | $ 1,170.00 |
Description | TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs. |
In vivo | TAT-Gap19 acetate (1 mg/kg/day) showed significantly decreased collagen deposition, as well as lower amounts of α-SMA-positive cells area in mice subjected to treatment with 100-200 mg thioacetamide (TAA)/kg body weight for eight weeks[1]. In 4 months old C57Bl6 male mice, TAT-Gap19 acetate (i.v.; 55 mg/kg) produces significant immune signal in the brain 24 h later[2]. |
Molecular Weight | 2703.25 |
Formula | C119H212N46O26 |
CAS No. | TP2110L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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TAT-Gap19 acetate TP2110L Cytoskeletal Signaling Gap Junction Protein TAT Gap19 acetate TAT-Gap19 Acetate TATGap19 acetate inhibitor inhibit