headache — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0203	Sumatriptan succinate	GR 43175	5-HT Receptor
	Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.		5-HT Receptor
TN2865	(E)-3,4,5-Trimethoxycinnamic acid	O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid	Others
	(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.		Others
TN1610	Epimagnolin A		Parasite
	Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion.		Parasite
T8414	SNC 80	Snc-80,SNC80,NIH 10815	Opioid Receptor
	SNC 80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist, Ki = 1.78 nM, IC50 = 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8 nM. SNC80 show...		Opioid Receptor
T26079	RI 61	RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61
	RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome.
TN6646	Fargesol
	(-)-Fargesol is a nartural product from the flowers buds of Magnolia fargesii,the dried flower buds of M. fargesii, has been used as therapy for nasal empyema and headache.
T69144	Hexylcaine HCl
	Hexylcaine HCl also called cyclaine or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and t...
T60345	Frovatriptan
	Frovatriptan is a highly potent agonist of the 5-HT 1B//D receptors, exhibiting the highest potency among triptan compounds. It possesses prominent cerebroselectivity. Frovatriptan demonstrates efficacy and even superior...
T31671	Erythrityl Tetranitrate	Eritrityli tetranitras,Tetranitrato de eritritilo,CHEBI:60072,Tetranitrate d'eritrityle
	Erythrityl Tetranitrate is a vasodilator with general properties similar to nitroglycerin. Like many nitrate esters, ETN acts as a vasodilator, and was the active ingredient in the original "sustained release" ...
T81584	Oxyresveratrol 4-O-β-D-glucopyranoside
	Oxyresveratrol 4-O-β-D-glucopyranoside (Compound 3) is a natural product extracted from the root bark of Morus atropurpurea, with potential applications in the research of diabetes, arthritis, rheumatism, cough, and head...
T60989	Sumatriptan hydrochloride
	Sumatriptan (GR 43175) hydrochloride can be used in the research of migraine headache that is an orally active agonist of 5-HT1 receptor. The Ki values of Sumatriptan hydrochloride against 5-HT1D, 5-HT1B and 5-HT1A rece...
T73631	(Rac)-SNC80
	(Rac)-SNC80, a racemate of SNC80 (NIH 10815), is a potent, highly selective non-peptide δ-opioid receptor agonist, characterized by a K_i of 1.78 nM and an IC_50 of 2.73 nM. Demonstrating antinociceptive, antihyperalgesi...
T79805	5-HT2 agonist-1 free base		5-HT Receptor
	Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. It is utilized in research pertaining to depression...		5-HT Receptor
T70070	Cisapride tartrate
	Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisa...
T14614	Biperiden Hydrochloride	KL 373 (Hydrochloride)	Others
	Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker and it is used for the adjunctive treatment of all forms of Parkinson's disease (pos...		Others