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Search Results for " ferritin "

7

Compounds

Cat No. Product Name Synonyms Targets
TP2248 ferritin heavy chain fragment [Multiple species] Others
Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21...
T13692 Ferric maltol Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate Others
Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations.
T20819 Ammonium iron(III) citrate Ferric ammonium citrate Others , Ferroptosis
Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellular iron death and enhances protein production.
T60202 MMRi62 7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol Ferroptosis
MMRi62 (7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol), a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity aga...
T26639 Ap44mSe
Ap44mSe is a potent and selective antitumor agent. Ap44mSe effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis ...
T73513 YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.
T71174 PBT434 HBr
PBT434 is a novel, brain-penetrant, small molecule inhibitor of α-synuclein aggregation. In transgenic animal models of Parkinson disease (A53T) and MSA (PLP-α-Syn), PBT434 reduced α-synuclein aggregation, preserved neur...
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