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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9564 | IRE1α kinase-IN-1 | IRE1 | |
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph... | |||
T11669 | IR415 | HBV | |
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i... | |||
T24098 | GP17 | GP-17,GP 17 | |
GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α. | |||
T24099 | GP29 | GP-29,GP 29 | |
GP29 is a Type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α. | |||
T63951 | ZINC000104379474 | ||
ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease. | |||
T38234 | HCoV-229E-IN-1 | ||
HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, demonstrating efficacy with an EC50 value of 0.65 μM in MTS cells and 0.6 μM in CPE cells[1]. |