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Search Results for " endoribonuclease "

6

Compounds

Cat No. Product Name Synonyms Targets
T9564 IRE1α kinase-IN-1 IRE1
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph...
T11669 IR415 HBV
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i...
T24098 GP17 GP-17,GP 17
GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
T24099 GP29 GP-29,GP 29
GP29 is a Type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
T63951 ZINC000104379474
ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.
T38234 HCoV-229E-IN-1
HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, demonstrating efficacy with an EC50 value of 0.65 μM in MTS cells and 0.6 μM in CPE cells[1].
TargetMol