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Search Results for " electrophysiology "

8

Compounds

Cat No. Product Name Synonyms Targets
T8372 VU0134992 VU 0134992 Potassium Channel
VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM
T13316 VU0134992 hydrochloride Potassium Channel
VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 µM).
T0030 Bupivacaine hydrochloride Vivacaine,Bupivacaine HCl Sodium Channel
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol...
T26862 BMS-902483
BMS-902483 is a potent α7 partial agonist. BMS-902483 improved cognition in preclinical rodent models. BMS-902483 showed FLIR α7 EC50=9.3nM; α7 Electrophysiology, rat; Area EC50 = 140 nM; Peak, Area (Ymax %) = 40, 54. 5-...
T26865 BMS-933043 BMS933043
BMS-933043 is a Selective α7 nAChR partial agonist. BMS-933043 showed potent binding affinity to native rat (Ki = 3.3 nM) and recombinant human alpha7 nicotinic acetylcholine receptors (Ki = 8.1 nM). BMS-933043 shows ago...
T37702 Pancuronium (bromide hydrate)
Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a n...
T4316 ML365 Potassium Channel
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).
T11377 GDC-0276 Others
GDC-0276, a potent, selective, reversible, and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM, offers potential for pain treatment while overcoming limitations associated with current pain medications, inclu...
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