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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83885 | DXR Inhibitor 11a sodium | 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a | |
DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum's growth in isol... | |||
T83908 | DXR Inhibitor 11a (free acid) | 1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a | |
DXR inhibitor 11a, with an IC50 of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrat... | |||
T78936 | Antimalarial agent 27 | Parasite | |
Antimalarial agent 27 (compound 11a) potently inhibits P. falciparum with an IC50 of 0.37 μM and targets the parasite's 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM, indicating its... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T17155 | Trabectedin | Ecteinascidin 743,ET-743 | Apoptosis , Reactive Oxygen Species |
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00557 | DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | |||
TMPH-01747 | FDXR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam... |