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Search Results for " dxr "

3

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T83885 DXR Inhibitor 11a sodium 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitor 11a
DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum's growth in isol...
T83908 DXR Inhibitor 11a (free acid) 1-Deoxy-D-Xylulose-5-phosphate Reductoisomerase Inhibitor 11a
DXR inhibitor 11a, with an IC50 of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also hampers the growth of P. falciparum in isolated human erythrocytes, demonstrat...
T78936 Antimalarial agent 27 Parasite
Antimalarial agent 27 (compound 11a) potently inhibits P. falciparum with an IC50 of 0.37 μM and targets the parasite's 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM, indicating its...
Cat No. Product Name Synonyms Targets
T17155 Trabectedin Ecteinascidin 743,ET-743 Apoptosis , Reactive Oxygen Species
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-00557 DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
TMPH-01747 FDXR Protein, Human, Recombinant (His & SUMO) Human E. coli
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam...
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