4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35480 | dBRD9-A | dBRD9-A | |
Potent BRD9 degrader. Selectively binds BRD9 and elicits near complete degradation of BRD9 at nanomolar concentrations. Inhibits growth of synovial sarcoma cells in vitro and tumor progression in a synovial sarcoma xeno... | |||
T31221 | dBRD9 | dBRD-9,dBRD 9 | PROTACs |
dBRD9 is a PROTAC. dBRD9 is a double-acting molecule, partially containing Bromodomain-containing protein 9 (BRD9), ligand that recruits the cereblon E3 ubiquitin ligase. Ligand that recruits the cereblon E3 ubiquitin li... | |||
T31221L | dBRD9 HCl | dBRD9 HCl(2170679-45-3 Free base) | Epigenetic Reader Domain |
dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl do... | |||
T39524 | Thalidomide-NH-PEG2-C2-NH-Boc | Thalidomide-NH-PEG2-C2-NH-Boc | |
Thalidomide-NH-PEG2-C2-NH-Boc, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon-targeting Thalidomide ligand with a PEG linker for the synthesis of dBRD9 (compound 6). This selective BRD9 probe PROT... |