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Search Results for " a-pyridone "

10

Compounds

Cat No. Product Name Synonyms Targets
T4805 α-Pyridone 2-Hydroxypyridine Others , Endogenous Metabolite
α-Pyridone (2-Hydroxypyridine)e is the catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.
T3080 Pyridone 6 Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I Tyrosine Kinases , JAK
Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM...
T60774 NITD-916 NITD916,NITD 916 Antibiotic
NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NA...
T71459 PD 163449
PD 163449 is a bioactive molecule of 4-pyridone group that inhibits bacterial type IIA topoisomerase (DNA gyrase and topoisomerase IV).
T34310 RG 14921 RG14921,RG-14921
RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.
T75455 Paecilomide
Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .
T29527 ABT-255 ABT 255,ABT255,UNII-YA04O24J4T
ABT-255 is a novel 2-pyridone antimicrobial agent for the treatment of tuberculosis. Both drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis showed efficacy in vitro and in vivo.
T38230 Iromycin A
Iromycin A is a bacterial pyridone metabolite that inhibits nitric oxide synthase (NOS) activity, with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS). Iromycin metabolites and derivatives block NADH ...
T64138 Cap-dependent endonuclease-IN-16
Cap-dependent endonuclease-IN-16 is a pyridone polycyclic derivative and a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN). cap-dependent endonuclease-IN-16 shows potential for influenza studies.
T83090 Anticancer agent 131
HCT-116-IN-1, a γ-lactam-fused pyridone derivative, exhibits anticancer properties, demonstrating significant cytotoxicity towards HCT116 cells, with an IC50 value of 5.59 μM [1].
TargetMol