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Search Results for " vismodegib "

2

Compounds

Cat No. Product Name Synonyms Targets
T2590 Vismodegib Erivedge,GDC-0449,RG 3616 Hedgehog/Smoothened , ABC , Autophagy
Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).
T70195 NL-103
NL-103 is a novel dual-targeted inhibitor of histone deacetylases and hedgehog pathway, effectively overcomes vismodegib resistance conferred by Smo mutations. NL-103 comprises structural elements of Hh pathway inhibito...
TargetMol