4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13336 | VTP50469 | Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase | |
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity. | |||
T13336L | VTP50469 fumarate | Others | |
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity. | |||
T69846 | VTP50469 mesylate | ||
VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations. | |||
T69845 | MX107 | ||
MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation. |