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Search Results for " trypanosoma "

20

Compounds

Cat No. Product Name Synonyms Targets
T63869 Anti-Trypanosoma cruzi agent-3
Anti-Trypanosoma cruzi agent-3 is an antiprotozoal agent.
T62333 Anti-Trypanosoma cruzi agent-1
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect.
T61114 Anti-Trypanosoma cruzi agent-2
Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC 50 = 0.51 μM) and INC-5 epimastigote form (IC 50 = 3.06 μM), posseses anti- T. gondii activity [1].
T72134 Anti-Trypanosoma cruzi agent-4
Anti-Trypanosoma cruzi Agent-4 is a Trypanosoma cruzi inhibitor utilized for the investigation of infections caused by this parasite.
T4S0590 Columbin Phospholipase , COX , Parasite
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion.
T3792 Ajugol Leonuride Parasite
Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).
T27135 DDD85646 DDD 85646,DDD-85646 Parasite
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
T4198 T.cruzi-IN-1 MDK1088,T.cruzi Inhibitor Antibiotic , Parasite
T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor.
T10340 Antitrypanosomal agent 2 Parasite
Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.
T10339 Antitrypanosomal agent 1 Parasite
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
T72229 Antitrypanosomal agent 11
Antitrypanosomal Agent 11 is a chemical compound effective against Trypanosoma cruzi, exhibiting an inhibition concentration (IC 50) of 0.23 μM.
T72228 Antitrypanosomal agent 10
Antitrypanosomal agent 10, an antitrypanosomal compound, effectively inhibits Trypanosoma cruzi with an IC50 of 0.28 μM.
T62372 Antitrypanosomal agent 8
Antitrypanosomal agent 8 (compound 3b) showed a strong antitrypanosomal effect against Trypanosoma brucei (IC50: 0.79 μM). The IC50 value was 80.95 μM.
T62212 Antitrypanosomal agent 4
Antitrypanosomal agent 4 (compound 19) is a potent antitrypanosomal agent that crosses the blood-brain barrier and shows good resistance to Trypanosoma cruzi and T. b. brucei with IC50 values of 1.2 μM and 70 nM respecti...
T62710 Antitrypanosomal agent 6
Antitrypanosomal agent 6 (compound 18a) is a potent antitrypanosomal agent showing good ADME properties. Antitrypanosomal agent 6 is more than twice as active as Nifurtimox against Trypanosoma brucei (T. brucei) with an ...
T79316 Antitrypanosomal agent 15 Proteasome
Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4 for T. cruzi and <4 for the human proteasome. It possesses ...
T83014 Antitrypanosomal agent 16 Parasite
Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T. congolense strain IL3000 [1].
T83012 Antitrypanosomal agent 18
Compound 18 (compound 8b), a nitrofuran derivative, exhibits potent in vitro trypanocidal activity, with an IC50 value of 0.03 μM [1].
T72267 Antitrypanosomal agent 9
Antitrypanosomal agent 9 is a potent compound with inhibitory activity against T. b. brucei, exhibiting an IC50 of 1.15 μM. It is utilized in research for human African trypanosomiasis (HAT).
T79254 Antitrypanosomal agent 14 Parasite
Antitrypanosomal agent 14 (Compound 1), a potent T. brucei inhibitor with an effective concentration (EC50) of 0.47 μM, also inhibits Tb GSK3 with an inhibitory concentration (IC50) of 12 μM, and is utilized in the resea...
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