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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63869 | Anti-Trypanosoma cruzi agent-3 | ||
Anti-Trypanosoma cruzi agent-3 is an antiprotozoal agent. | |||
T62333 | Anti-Trypanosoma cruzi agent-1 | ||
Anti-Trypanosoma cruzi agent-1 (Compd E5) has a potent anti-Toxoplasma effect. | |||
T61114 | Anti-Trypanosoma cruzi agent-2 | ||
Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC 50 = 0.51 μM) and INC-5 epimastigote form (IC 50 = 3.06 μM), posseses anti- T. gondii activity [1]. | |||
T72134 | Anti-Trypanosoma cruzi agent-4 | ||
Anti-Trypanosoma cruzi Agent-4 is a Trypanosoma cruzi inhibitor utilized for the investigation of infections caused by this parasite. | |||
T4S0590 | Columbin | Phospholipase , COX , Parasite | |
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |||
T3792 | Ajugol | Leonuride | Parasite |
Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml). | |||
T27135 | DDD85646 | DDD 85646,DDD-85646 | Parasite |
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM. | |||
T4198 | T.cruzi-IN-1 | MDK1088,T.cruzi Inhibitor | Antibiotic , Parasite |
T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor. | |||
T10340 | Antitrypanosomal agent 2 | Parasite | |
Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei. | |||
T10339 | Antitrypanosomal agent 1 | Parasite | |
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM). | |||
T72229 | Antitrypanosomal agent 11 | ||
Antitrypanosomal Agent 11 is a chemical compound effective against Trypanosoma cruzi, exhibiting an inhibition concentration (IC 50) of 0.23 μM. | |||
T72228 | Antitrypanosomal agent 10 | ||
Antitrypanosomal agent 10, an antitrypanosomal compound, effectively inhibits Trypanosoma cruzi with an IC50 of 0.28 μM. | |||
T62372 | Antitrypanosomal agent 8 | ||
Antitrypanosomal agent 8 (compound 3b) showed a strong antitrypanosomal effect against Trypanosoma brucei (IC50: 0.79 μM). The IC50 value was 80.95 μM. | |||
T62212 | Antitrypanosomal agent 4 | ||
Antitrypanosomal agent 4 (compound 19) is a potent antitrypanosomal agent that crosses the blood-brain barrier and shows good resistance to Trypanosoma cruzi and T. b. brucei with IC50 values of 1.2 μM and 70 nM respecti... | |||
T62710 | Antitrypanosomal agent 6 | ||
Antitrypanosomal agent 6 (compound 18a) is a potent antitrypanosomal agent showing good ADME properties. Antitrypanosomal agent 6 is more than twice as active as Nifurtimox against Trypanosoma brucei (T. brucei) with an ... | |||
T79316 | Antitrypanosomal agent 15 | Proteasome | |
Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4 for T. cruzi and <4 for the human proteasome. It possesses ... | |||
T83014 | Antitrypanosomal agent 16 | Parasite | |
Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T. congolense strain IL3000 [1]. | |||
T83012 | Antitrypanosomal agent 18 | ||
Compound 18 (compound 8b), a nitrofuran derivative, exhibits potent in vitro trypanocidal activity, with an IC50 value of 0.03 μM [1]. | |||
T72267 | Antitrypanosomal agent 9 | ||
Antitrypanosomal agent 9 is a potent compound with inhibitory activity against T. b. brucei, exhibiting an IC50 of 1.15 μM. It is utilized in research for human African trypanosomiasis (HAT). | |||
T79254 | Antitrypanosomal agent 14 | Parasite | |
Antitrypanosomal agent 14 (Compound 1), a potent T. brucei inhibitor with an effective concentration (EC50) of 0.47 μM, also inhibits Tb GSK3 with an inhibitory concentration (IC50) of 12 μM, and is utilized in the resea... |