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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5150 | Treprostinil | LRX-15,Orenitram,Remodulin | Prostaglandin Receptor |
Treprostinil (Orenitram) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM). | |||
T5171 | Treprostinil Sodium | UT-15 | VEGFR , c-RET , Prostaglandin Receptor |
Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM). | |||
T63349 | Treprostinil diethanolamine | UT-15C | Prostaglandin Receptor |
Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FPKi, respectively. Treprostinil diethanolamine i... | |||
T39165 | Treprostinil palmitil | Treprostinil palmitil,INS-1009 | |
Treprostinil Palmitil (TP), a prodrug of the DP1 and EP2 agonist Treprostinil (UT-15), exhibits EC50 values of 0.6 and 6.2 nM, respectively. It is a pure prodrug without any inherent binding affinity for G-protein couple... | |||
T36210 | 15-keto Treprostinil (sodium salt) | ||
15-keto Treprostinil is an impurity found in treprostinil , which is a stable analog of prostaglandin I2 with a longer plasma half-life. Formulations containing treprostinil are used for the treatment of primary pulmonar... | |||
TN7246 | 3-Sulfopropanoic acid | 3-SPA | Drug Metabolite |
3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD patients that inhibits the formation of Aβ42 oligomers. |