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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0179 | Ticagrelor | AR-C 126532XX,AZD6140 | P450 , P2Y Receptor |
Ticagrelor (AR-C 126532XX), produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European U... | |||
T21059 | Ticagrelor metabolite M5 | Ticagrelor metabolite M5,,T437700,AR-C133913XX | P2Y Receptor |
Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ti... | |||
T82898 | Bentracimab | PB 2452,MEDI 2452 | |
Bentracimab (PB 2452) is a monoclonal antibody that effectively neutralizes Ticagrelor and its primary active metabolite by binding with high affinity, facilitating the rapid reversal of Ticagrelor's antiplatelet effects... | |||
T63334 | Antiplatelet agent 1 | ||
Antiplatelet agent 1 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies. | |||
T63335 | Antiplatelet agent 2 | ||
Antiplatelet agent 2 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies. | |||
T75242 | Bivalirudin TFA | ||
Bivalirudin TFA, a synthetic 20-residue peptide, serves as a reversible inhibitor of thrombin. Its IC50 value highlights its target specificity in vitro, where, combined with Eptifibatide (8 mg/mL) at a low concentration... |