tbk1/ikkε-in-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13097	TBK1/IKKε-IN-1		IκB/IKK
	TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).		IκB/IKK
T7951	TBK1/IKKε-IN-5		IκB/IKK
	TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).		IκB/IKK
T15559	TBK1/IKKε-IN-2		IκB/IKK
	TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.		IκB/IKK
T38263	TBK1/IKKε-IN-4	TBK1/IKKε-IN-4
	TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced ...
T39841	TBK1/IKKε-IN-6	TBK1/IKKε-IN-6
	TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.
T0097	MRT67307	MRT67307 HCl	IκB/IKK , Autophagy
	Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...		IκB/IKK , Autophagy
T23028	MRT67307 HCl (1190378-57-4 free base)	MRT67307 HCl	Others
	MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it i...		Others