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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2121 | Sauvagine | ||
Corticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively. | |||
T75894 | Sauvagine TFA | ||
Sauvagine TFA, a mammalian CRF agonist derived from a 40-amino-acid neuropeptide found in frog skin, effectively releases ACTH from rat pituitary cells. It exhibits pharmacological effects on diuresis, the cardiovascular... | |||
TP2091 | Antisauvagine-30 | ||
Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAM... | |||
T75805 | Antisauvagine-30 TFA | ||
Antisauvagine-30 TFA (aSvg-30 TFA), a potent peptidic antagonist specific to the CRF 2 receptor, demonstrates high selectivity and competitive interaction. It shows dissociation constants (Kd) of 1.4 nM for mCRFR2β and 1... | |||
T10338 | Antisauvagine-30 TFA (220673-95-0 free base) | Antisauvagine-30 TFA,aSvg-30 TFA | Others |
Antisauvagine-30 TFA (aSvg-30 TFA) is a highly selective and competitive antagonist of CRF2 receptor peptidic. It shows a Kd of 1.4 nM and 150 nM for mCRFR2β and CRFR1, respectively. | |||
TP2009L | K 41498 aceate | CRFR | |
K41498 acetate, an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. K41498 acetate is a potent and highly selective antagonist CRF2 receptor... | |||
TP2009 | K41498 | K 41498 | |
Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-exp... | |||
T75804 | K41498 TFA | ||
K41498 TFA, an analog of antisauvagine-30 (aSvg-30), is a potent and highly selective antagonist of CRF2 receptors, exhibiting K i values of 0.66 nM, 0.62 nM, and 425 nM for human CRF 2α, CRF 2β, and CRF 1 receptors, res... | |||
T36373 | Urocortin II (mouse) (trifluoroacetate salt) | ||
Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II... | |||
T35814 | Urocortin III (human) (trifluoroacetate salt) | ||
Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin II... |