Search Result

Search Results for " stat5b "

Compounds

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T70148	CDK8-IN-4k
	CDK8-IN-4k is a potent and highly selective CDK8 inhibitor, with no apparent potential for time-dependent CYP3A4 inhibition.
T24838	Stafib-1	Stafib 1,Stafib1	STAT
	Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 nM and a Ki of 44 nM.		STAT
T9646	Stafib-2		STAT
	Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM, respectively.Stafib-2 has poor cell permeability.		STAT
T9339	Stafia-1		STAT
	Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.		STAT
T70150	Capstafin
	Capstafin is a highly potent and selective inhibitor of STAT5b.
T70149	PomCapstafin
	PomCapstafin is a prodrug of Capstafin, acting as a potent, selective STAT5b inhibitor.
T71156	Poloxipan
	Poloxipan is a potent and pan-specific PLK1 inhibitor. In vitro, Poloxipan has IC50 3.2 uM (Plk1); 1.7 uM (Plk2); and 3 uM (Plk3). Poloxipan showed minor inhibition over FHA dommain of Chk2, S2 domian of STAT1, STAT5b, L...
T73739	Pomstafib-2
	Pomstafib-2, a potent and selective inhibitor of STAT5b, reduces pSTAT5b expression and effectively induces apoptosis [1] [2].
T62496	IST5-002
	IST5-002 is a potent inhibitor of Stat5a/b and selectively inhibits the transcriptional activity of Stat5a/b with IC50 values of 1.5 μM and 3.5 μM for Stat5a and Stat5b, respectively. IST5-002 can be used to study prosta...

Compounds

Synonym: Stafib 1,Stafib1

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-01003	STAT5B Protein, Human, Recombinant (His)	Human	E. coli
	Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differ...
TMPU-00004	STAT5A Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate canc...
TMPH-02274	JAK2 Protein, Human, Recombinant (His)	Human	E. coli
	Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto...

STAT5B Protein, Human, Recombinant (His)

TMPJ-01003

Species: Human

Expression System: E. coli

STAT5A Protein, Human, Recombinant (His)

TMPU-00004

Species: Human

Expression System: E. coli

JAK2 Protein, Human, Recombinant (His)

TMPH-02274

Species: Human

Expression System: E. coli

Cat No.	Product Name
L3700	JAK-STAT Compound Library		252 compounds
	A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;

Libraries

JAK-STAT Compound Library

L3700

Compounds: 252