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Search Results for " smyd3 "

9

Compounds

Cat No. Product Name Synonyms Targets
T12940 SMYD3-IN-1 Histone Methyltransferase
SMYD3-IN-1 is an irreversible and selective SMYD3 (SET and MYND domain containing 3) inhibitor(IC50 of 11.7 nM).
T73183 SMYD3-IN-2
SMYD3-IN-2, a potent inhibitor of SMYD3, demonstrates significant efficacy in combating gastric cancer by promoting lethal autophagy. It exhibits strong inhibitory activity against both SMYD3 and BGC823 cells, with IC 50...
T36631 BAY-6035 MEK , Histone Methyltransferase
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.
TQ0263 EPZ031686 EPZ-031686 Histone Methyltransferase
EPZ031686 is an effective inhibitor of SMYD3 inhibitor with an IC50 of 3 nM and can be used in studies about cancer.
T60777 EM127 ERK , Histone Methyltransferase
EM127 is a highly selective and potent covalent inhibitor of SMYD3 with a KD value of 13 μM.EM127 inhibits ERK1/2 phosphorylation and inhibits transcriptional regulation of SMYD3 target genes.EM127 slowly reduces methylt...
T11486 GSK2807 Trifluoroacetate Histone Methyltransferase
GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).
T5322 BCI-121 Histone Methyltransferase
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.
T24038 EPZ-030456
EPZ-030456 is an effective and selective inhibitor of the SMYD3.
T69738 GSK-2807 free base
GSK2807 is a potent and selective, SAM-competitive inhibitor of SMYD3 (Ki = 14 nM). GSK2807 bridges the gap between the SAM-binding pocket and the substrate lysine tunnel of SMYD3. GSK2807 may be useful for cancer trea...
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