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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12940 | SMYD3-IN-1 | Histone Methyltransferase | |
SMYD3-IN-1 is an irreversible and selective SMYD3 (SET and MYND domain containing 3) inhibitor(IC50 of 11.7 nM). | |||
T73183 | SMYD3-IN-2 | ||
SMYD3-IN-2, a potent inhibitor of SMYD3, demonstrates significant efficacy in combating gastric cancer by promoting lethal autophagy. It exhibits strong inhibitory activity against both SMYD3 and BGC823 cells, with IC 50... | |||
T36631 | BAY-6035 | MEK , Histone Methyltransferase | |
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases. | |||
TQ0263 | EPZ031686 | EPZ-031686 | Histone Methyltransferase |
EPZ031686 is an effective inhibitor of SMYD3 inhibitor with an IC50 of 3 nM and can be used in studies about cancer. | |||
T60777 | EM127 | ERK , Histone Methyltransferase | |
EM127 is a highly selective and potent covalent inhibitor of SMYD3 with a KD value of 13 μM.EM127 inhibits ERK1/2 phosphorylation and inhibits transcriptional regulation of SMYD3 target genes.EM127 slowly reduces methylt... | |||
T11486 | GSK2807 Trifluoroacetate | Histone Methyltransferase | |
GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM). | |||
T5322 | BCI-121 | Histone Methyltransferase | |
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell. | |||
T24038 | EPZ-030456 | ||
EPZ-030456 is an effective and selective inhibitor of the SMYD3. | |||
T69738 | GSK-2807 free base | ||
GSK2807 is a potent and selective, SAM-competitive inhibitor of SMYD3 (Ki = 14 nM). GSK2807 bridges the gap between the SAM-binding pocket and the substrate lysine tunnel of SMYD3. GSK2807 may be useful for cancer trea... |