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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12928 | SK33 | Androgen Receptor | |
SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity. | |||
T5745 | GSK3326595 | EPZ015938 | Histone Methyltransferase |
GSK3326595 (EPZ015938) is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.). | |||
T11500L | GSK3368715 dihydrochloride | EPZ019997 dihydrochloride,GSK3368715 2HCl,EPZ019997 2HCl | Histone Methyltransferase |
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs) with anticancer and antitumor activity, inhibiting PRMT1, PRMT3, PRMT4... | |||
T15439 | GSK3395879 | TRP/TRPV Channel | |
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4). | |||
T22342 | GSK3368715 3HCl | EPZ019997 3HCl,GSK3368715(EPZ019997) | Histone Methyltransferase |
GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM. | |||
T27473 | GSK334429 | GSK-334429,GSK 334429 | |
GSK334429 is an antagonist of histamine H3 receptor. | |||
T11500 | GSK3368715 | EPZ019997 | Histone Methyltransferase |
GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRM... |