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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T41226 | SIM1 | ||
SIM1 is a potent and selective trivalent PROTAC®Degrader based on BET bromodomain inhibitors linked to a Von Hippel Lindau (VHL) ligand via branched linkers. SIM1 degrades all BET family proteins with a preference for BR... | |||
T41199 | Cis-SIM1 | cis-SIM1 | |
cis-SIM1 is the negative control for SIM1. | |||
T17252 | SIM-688 | SIM688 | Estrogen/progestogen Receptor , NF-κB |
SIM-688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50 = 122 nM in HAECT-1 cells). |