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Search Results for " ret-in-10 "

3

Compounds

Cat No. Product Name Synonyms Targets
T63782 RET-IN-10
RET-IN-10 is a potent inhibitor of RET, in which RET loss-of-function mutations cause congenital megacolon and its gain-of-function mutations are associated with a variety of human tumors. RET-IN-10 has shown research po...
T16995 TAS05567 FLT , c-RET , JAK , Syk
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM). TAS05567 only shows >70% inhibition of Syk and 4 other kinases (FLT3, JAK2, KDR, and RET with IC50s of 10 nM, 4.8 nM, 600 nM, and...
T78871 PLM-101
PLM-101 is an anticancer compound orally active against acute myeloid leukemia by targeting FLT3 and RET. It impedes RET function, promoting autophagic breakdown of FLT3, and suppresses the PI3K and Ras/ERK pathways, con...
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