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Search Results for " rad51-in-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T9271 RAD51-IN-1 DNA/RNA Synthesis
Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
T6972 RS-1 DNA/RNA Synthesis
RS-1 is a RAD51 activator. RS-1 also increases CRISPR/Cas9-mediated knock-in efficiencies.
T61469 RAD51-IN-8
RAD51-IN-8, a new RAD51 binder, is a RAD51-BRCA2 inhibitor that inhibits the RAD51 BRCA2 protein protein interaction in the micromolar range. RAD51-IN-8 also is a protein protein interaction (PPI) inhibitor. RAD51-IN-8 h...
T28536 RI(dl)-2 TFA RI(dl)-2
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM which also inhibits homologous recombination(HR) activity in human cells with IC50 of 3.0 μM[1].
T36703 CAY10760
CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing Bx...
T74501 NHEJ inhibitor-1
NHEJ Inhibitor-1 (Compound C2), a trifunctional Pt(II) complex, mitigates non-homologous end joining (NHEJ)/homologous recombination (HR)-related double strand break (DSB) repairs, combating Cisplatin resistance in non-s...
T83854 BRC4wt TFA
BRC4wt, an acetylated peptide originating from the BRC4 repeat within human BRCA2 (1521-1536), acts as an inhibitor of the BRCA2 and RAD51 protein-protein interaction. When linked to the cationic cell-penetrating peptide...
T36701 Phosphoramide mustard (cyclohexanamine)
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA d...
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