3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8464 | RA-9 | Apoptosis , DUB | |
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines. | |||
T23087 | NPY 5RA972 | Neuropeptide Y Receptor | |
neuropeptide Y Y5 receptor antagonist | |||
T64049 | KIRA9 | ||
KIRA9 is a potent inhibitor of IRE1 with an IC50 value of 4.8 μM for INS-1 cells. KIRA9 completely binds the ATP binding site of IRE1 and blocks endoplasmic reticulum (ER) localised mRNA decay and apoptosis. |