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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T29089 | Valategrast hydrochloride | Valategrast HCl,R411,RO0272441,RO27244,RO-27-2441,R-411,RO-0272441 | Integrin |
Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma. | |||
T13277 | Valategrast | R-411 free base | Others |
Valategrast is a potent and orally active dual antagonist of integrin α4β1 (VLA-4) and α4β7, with the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment. | |||
T40775 | SSR411298 | SSR411298 | |
SSR411298 is a reversible, orally active compound that selectively inhibits fatty acid amide hydrolase (FAAH). Its potential lies in the field of post-traumatic stress disorder (PTSD) research. | |||
T36716 | RO0270608 | RO0270608 | |
RO0270608, the active metabolite of R411, is a dual α4β1/α4β7 integrin antagonist with anti-inflammatory activity[1][2]. |