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Search Results for " r112 "

4

Compounds

Cat No. Product Name Synonyms Targets
T3185 R112 (E)-Elafibranor Syk
R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.
T10965 DBPR112 EGFR
DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor eff...
T23383 SR11237 SR 11237 Others , RAR/RXR 
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
T69498 DBPR112 HCl
DBPR112 is a potent EGFR inhibitor (IC50=487 nM) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer. DBPR112), DBPR112 not only displayed a potent inhibitory activity against EGFRL858R/T790M double ...
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