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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16605 | Propargyl-PEG3-acid | PROTAC Linker | |
Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker. Propargyl-PEG3-acid is also a PEG-based PROTAC linker used to synthesize 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA and Propargyl-PEG3-acid[1]. | |||
T16612 | Propargyl-PEG3-phosphonic acid | Others | |
Propargyl-PEG3-phosphonic acid, a PEG-based PROTAC linker, is utilized for PROTAC synthesis[1]. | |||
T16611 | Propargyl-PEG3-phosphonic acid diethyl ester | Others | |
Propargyl-PEG3-phosphonic acid diethyl ester, a PEG-based PROTAC linker, is employed for the synthesis of PROTACs[1]. | |||
T16620 | Propargyl-PEG5-acid | Propargyl-PEG4-C2-acid | Others |
Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3[1]. | |||
T16614 | Propargyl-PEG4-acid | Others | |
Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib -based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1]... |