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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6960 | PU-H71 | HSP | |
PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM. | |||
T6960L | PU-H71 HCl | PU-H71 HCl(873436-91-0 Free base),Zelavespib HCl | HSP , DNA/RNA Synthesis |
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of maligna... | |||
T71247 | PU-H71 hydrate | ||
PU-H71 hydrate is a potent inhibitor of heat shock protein 90 (Hsp90). | |||
T80742 | Zelavespib hydrochloride | PU-H71 hydrochloride | HSP |
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 nM in MDA-MB-468 cells. | |||
T71245 | ARRY-502 | ||
ARRY-502 is a CRTH2 antagonist. Regulation of cytokine activity is important in molecularly targeted therapies for asthma. | |||
T69712 | Icapamespib HCl | ||
Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ... | |||
T70270 | SMTIN-P01 | ||
SMTIN-P01 is a mitochondria-targeted Hsp90 inhibitor. It is made from the isopropyl amine of the Hsp90 inhibitor PU-H71 being replaced with the mitochondria-targeting moiety triphenylphosphonium. |