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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15782 | Lp-PLA2-IN-1 | Lp-PLA2 inhibitor 1,Lp-PLA2 -IN-1 | Phospholipase |
Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) suppresses Lp-PLA2 activity processes for their preparation. Lp-PLA2-IN-1 (Lp-PLA2 inhibitor 1) also inhibits to compositions containing them and to their use in the treatment of diseas... | |||
T11874 | Lp-PLA2-IN-3 | Phospholipase | |
Lp-PLA2-IN-3 is a potent and orally bioactive lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor that inhibits recombinant human Lp-PLA2 with an IC50 value of 14 nM. | |||
T11873 | Lp-PLA2-IN-2 | Phospholipase | |
Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2. | |||
T79076 | Lp-PLA2-IN-16 | Phospholipase | |
Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1]. | |||
T79075 | Lp-PLA2-IN-15 | Phospholipase | |
Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1]. | |||
T79074 | Lp-PLA2-IN-14 | Phospholipase | |
Lp-PLA2-IN-14 (Compound 19), an inhibitor of rhLp-PLA2, exhibits a potent inhibitory effect with a pIC50 value of 8.4. This compound is applicable in research pertaining to neurodegenerative disorders, including Alzheime... | |||
T62947 | Lp-PLA2-IN-11 | ||
Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2-IN-11 has the potential to be investigated in diseases associated with Lp-PLA2 activity (e.g. atherosclerosis, Alzheimer's... | |||
T63345 | Lp-PLA2-IN-5 | ||
Lp-PLA2-IN-5 is a potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-5 has the potential to be studied in diseases associated with Lp-PLA2 activity, such as Alzheimer's disease, atherosclerosi... | |||
T63633 | Lp-PLA2-IN-6 | ||
Lp-PLA2-IN-6 is a tetracyclic pyrimidinone compound that is a potent inhibitor of Lp-PLA2 and is able to act on rhLp-PLA2 (pIC50: 10.0). lp-PLA2-IN-6 has shown research potential in neurodegenerative diseases. | |||
T63931 | Lp-PLA2-IN-9 | ||
Lp-PLA2-IN-9 (compound 17) is a tetracyclic pyrimidinone compound, a potent inhibitor of Lp-PLA2 that acts on rhLp-PLA2 (pIC50: 10.1). lp-PLA2-IN-9 has shown research potential in neurodegenerative diseases. | |||
T79073 | Lp-PLA2-IN-13 | Phospholipase | |
Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1]. | |||
T63344 | Lp-PLA2-IN-4 | ||
Lp-PLA2-IN-4 is a potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2-IN-4 has the potential to be studied in diseases associated with Lp-PLA2 activity, such as Alzheimer's disease, atherosclerosi... | |||
T79010 | Lp-PLA2-IN-12 | Phospholipase | |
Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), and cardiovascular conditions... | |||
T63192 | Lp-PLA2-IN-10 | ||
Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), formerly known as platelet-activating factor acetylhydrolase (PAF-AH). This enzyme plays a role in the hydrolysis of lipoprotein l... | |||
T2044 | Varespladib | LY315920 | Phospholipase |
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv... | |||
TMO2790 | 1-Naphthaleneacetic acid | Transplantone,1-Naphthylacetic acid,α-Naphthaleneacetic acid,Phyomone | Phospholipase |
1-Naphthaleneacetic acid (Transplantone) , is widely used in agriculture for various purposes. It is a synthetic plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural produ... | |||
T5580 | 1-Naphthaleneacetic acid potassium salt | α-Naphthaleneacetic acid,Potassium alpha-naphthylacetate,Potassium 1-Naphthaleneacetate,1-NAA Potassium Salt | Phospholipase |
1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) is used as a plant Growth Regulator that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fu... | |||
T12990 | SPLA2-X Inhibitor 31 | Others | |
sPLA2-X Inhibitor 31 is a selective inhibitor of secreted phospholipase A2 type X (sPLA2-X) (IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively). | |||
T27731 | SPLA2 inhibitor 1 | KH-064,KH 064,KH064,5-BPP acid | |
KH064 is a sPLA2-IIA inhibitor of oral activity. | |||
T81115 | SPLA2-IIA Inhibitor | ||
The sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2), which interacts with human IIA phospholipase A2 (hGIIA) to impede its ester bond hydrolyzing function. A... |