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Search Results for " phd3 "

6

Compounds

Cat No. Product Name Synonyms Targets
T81494 PhD3
PhD3, an antimicrobial peptide originating from monkey leukocytes, exhibits potent activity against various bacteria and the fungus Candida albicans [1].
T29797 AKB-6899 AKB6899 VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which in...
T5392 TP0463518 HIF/HIF Prolyl-Hydroxylase
TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).
T3180 JNJ-42041935 HIF-PHD Inhibitor II HIF/HIF Prolyl-Hydroxylase
JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.
T4106 MK-8617 MK8617 HIF/HIF Prolyl-Hydroxylase
MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).
T61458 HIF-PHD-IN-2
HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].
TargetMol