pge1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T29908	Alprostadil ethyl ester	Prostaglandin E1 ethyl ester,PGE1 ethyl ester
	Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.
T29907	Alprostadil sodium	PGE1 sodium salt,Prostaglandin E1 sodium
	Alprostadil sodium is a prostaglandin receptor ligand with Ki values of 36, 10, 1.1, 2.1, and 33 nM for EP1, EP2, EP3, EP4, and IP, respectively, in mice.It induces vasodilatation and inhibits platelet aggregation, and i...
T15757	Limaprost	17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206	PGE Synthase
	Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood...		PGE Synthase
T36775	13,14-dihydro Prostaglandin E1	13,14-dihydro Prostaglandin E1
	13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and wash...
T36726	6-keto Prostaglandin E1	6-keto Prostaglandin E1
	6-keto Prostaglandin E1 is a bioactive derivative of PGE1 that plays a role in antiplatelet aggregation and depolymerization.
T34550	SC 31391	SC31391,SC-31391
	SC 31391 is a PGE1 analog.
T73346	SC 34301	Enisoprost
	SC 34301 (Enisoprost), a potent and orally active prostaglandin E1 (PGE1) analog, significantly enhances survival rates and reduces bacterial translocation in burned mice.
T36147	13,14-dihydro-15-keto Prostaglandin E1	13,14-dihydro-15-keto Prostaglandin E1
	13,14-dihydro-15-keto Prostaglandin E1 inhibits ADP-induced platelet aggregation in human isolated platelet-rich plasma (IC50=14.8 μg/mL) and is a PGE1 metabolite.
TQ0262	Dihomo-γ-linolenic acid	Diroleuton,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989	Others
	Ro 12-1989 can be converted into prostaglandin E1 (PGE1). Ro 12-1989 competes with arachidonic acid for COX and lipoxygenase, inhibiting the production of arachidonic acid's eicosanoids.		Others
T36214	16,16-dimethyl Prostaglandin E1	16,16-dimethyl Prostaglandin E1
	16,16-dimethyl Prostaglandin E1 is a PGE1 (T1626) analog that induces bronchoconstriction and vascular smooth muscle contraction and inhibits indomethacin-induced cell elongation.
T36154	15(S)-15-methyl Prostaglandin E2	15(S)-15-methyl Prostaglandin E2
	15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound. 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is te...
T36209	15-keto Prostaglandin A1	15-keto Prostaglandin A1
	Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 ...
T37773	Tetranor-PGEM	tetranor-Prostaglandin E Metabolite,tetranor-PGEM
	tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy ...
T36157	8-iso Prostaglandin A1	8-iso Prostaglandin A1
	8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane and a member in a large family of prostanoids of non-cyclooxygenase origin. It occurs as a common minor impurity in most commercial preparations of PGE1. The biologic...
T70865	BMY-42393
	BMY-42393 is orally active and selective platelet aggregation inhibitor. BMY-42393 is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation (IC50 range 0.3 - 2.0 mic...
T36167	8-iso-15-keto Prostaglandin F2β	8-iso-15-keto Prostaglandin F2β
	8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits ...
T37233	(±)14(15)-EpEDE
	8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid , is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases. It can be metabolized by the cyclooxygenas...
T62532	MRS2395
	MRS2395 is a dipivaloyl derivative and a potent antagonist of the P2Y12 receptor. MRS2395 inhibited ADP-induced platelet activation (Ki: 3.6 μM). MRS2395 enhances platelet dense granule release in response to TRAP-6.
T83807	Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium	Rp-ATP-α-S
	Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 recept...