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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19965 | Dacomitinib hydrate | PF 299804,PF00299804,PF 00299804,PF-00299804,PF299804,PF-299804 | EGFR |
Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds... | |||
T2483 | Dacomitinib | PF-299804,PF-00299804,PF299 | Apoptosis , EGFR |
Dacomitinib (PF299)(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respective... |