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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28363 | PF-02545920 | ||
PF-02545920, a PDE10 inhibitor, is used potentially for the treatment of Huntington's Disease. | |||
T62356 | Mardepodect hydrochloride | PF-2545920 HCl,Mardepodect HCl,MP-10 HCl,PF-02545920 HCl | Apoptosis , PDE |
Mardepodect hydrochloride (Mardepodect HCl) is an orally active, selective and potent inhibitor of PDE10A that crosses the blood-brain barrier (IC50: 0.37 nM).Mardepodect hydrochloride up-regulates the expression of prot... | |||
T16499 | Mardepodect | PF-2545920 | PDE |
Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE. It is potentially useful for the treatment of schizophrenia. Phosphodie... |