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Search Results for " perk-in-6 "

4

Compounds

Cat No. Product Name Synonyms Targets
T72053 PERK-IN-6 PERK
PERK-IN-6 is a novel and highly potent PERK inhibitor (IC50:2.5 nM).
T11374 GCN2-IN-6 Others , PERK
GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6  is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8...
T10299 AMG PERK 44 PERK , Autophagy
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy.AMG PERK 44 inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM) and can be used in the study of cancer.
T79072 KRAS G12D modulator-1 Ras
KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is utilized in cancer research [1].
TargetMol