pd-1/pd-l1-in-8 — TargetMol Chemicals

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Search Results for " pd-1/pd-l1-in-8 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T36899	INCB086550	PD-1/PD-L1-IN-8	PD-1/PD-L1
	INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.		PD-1/PD-L1
T61968	PD-1/PD-L1-IN 6
	PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1...
T40112	PROTAC PD-1/PD-L1 degrader-1	PROTAC PD-1/PD-L1 degrader-1
	PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr...
T79068	TLR7/8 agonist 8
	TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8)...
T74348	HE-S2		PD-1/PD-L1
	HE-S2, an antibody-drug conjugate, elicits a potent antitumor immune response by inhibiting the PD-1/PD-L1 interaction and stimulating the Toll-like receptor 7/8 (TLR7/8) signaling pathway, resulting in significant antit...		PD-1/PD-L1
T79069	TLR7/8 agonist 9
	TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the efficacy of PD-1/PD-L1 blockade treatments. This compound i...