9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79559 | Mtb-IN-4 | ||
Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity, with an IC50 value of 0.70 μM. It impedes Mtb respiration and biofilm formation within macrophages and augmen... | |||
T72300 | Mtb-cyt-bd oxidase-IN-4 | ||
Mtb-cyt-bd oxidase-IN-4, an inhibitor of Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase), demonstrates potent activity with an IC50 value of 0.25 μM and inhibits the growth of Mycobacterium tubercul... | |||
T67765 | MenA-IN-2 | Others | |
MenA-IN-2 is a potent 1, 4-dihydroxy-2-naphthoate isopentadiene transferase (MenA) inhibitor with an IC50 value of 22 µM for MenA and 10 µM for Mycobacterium tuberculosis (Mtb). The continuous transmission of MenA-IN-2 M... | |||
T72302 | Mtb-cyt-bd oxidase-IN-6 | ||
Mtb-cyt-bd oxidase-IN-6, a potent inhibitor of Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase), exhibits an inhibitory concentration (IC50) of 0.35 μM and effectively suppresses Mtb gr... | |||
T61395 | Mt KARI-IN-4 | ||
Mt KARI-IN-4 (compound 5c) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), demonstrating a Ki value of 5.48 μM. Additionally, Mt KARI-IN-4 displays inhibitory propert... | |||
T79440 | DprE1-IN-5 | ||
DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates antimycobacterial efficacy against drug-resistant strains. Additionally, it ... | |||
T78714 | PptT-IN-4 | Calcium Channel | |
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM. It also demonstrates antimycobacterial activity against Mtb H37Rv, with a MIC of 42 μM, and inhibits hERG, hCav1.2, and hNav1.5 channels with IC5... | |||
T79441 | DprE1-IN-6 | ||
DprE1-IN-6 (Compound 56) is a DprE1 inhibitor with demonstrated anti-TB activity, exhibiting a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain, along with efficacy against drug-resistant mycob... | |||
T79442 | DprE1-IN-7 | ||
DprE1-IN-7 (Compound 64) is a DprE1 inhibitor with potent anti-tuberculosis (TB) activity, demonstrating a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain. It exhibits antimycobacterial effect... |