mdm2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T72026	P53-MDM2-IN-1		Mdm2 , p53
	p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM. This compound holds potential for applications in anti-tumor research.		Mdm2 , p53
T67698	P53-Mdm2 inhibitor 4		Mdm2 , p53
	p53-Mdm2 inhibitor 4 inhibits the p53-MDM2 protein-protein interaction.		Mdm2 , p53
T41084	MDM2-IN-21	MDM2-IN-21
	MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer.
T24440	MDM2-p53-IN-1b	MDM2-p53 inhibitor 1b,MDM2 p53 IN 1b
	MDM2-p53-IN-1b is the MDM2-p53 interaction inhibitor.
T12351	P53 and MDM2 proteins-interaction-inhibitor (racemic)	p53-and-mdm2-proteins-interaction-inhibitor-racemic	Others
	p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins.		Others
T18633	PROTAC MDM2 Degrader-3		Others
	PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].		Others
T11982	MDM2-IN-1		Others
	MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.		Others
T18632	PROTAC MDM2 Degrader-2		Others
	PROTAC MDM2 Degrader-2 is a compound designed utilizing PROTAC technology, functioning as a MDM2 degrader. Comprised of a highly potent inhibitor targeting MDM2, a linker, and the MDM2 ligand for E3 ubiquitin ligase, thi...		Others
T18634	PROTAC MDM2 Degrader-4		Others
	PROTAC MDM2 Degrader-4 is a compound designed using PROTAC technology to degrade MDM2. It combines a powerful MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].		Others
T18631	PROTAC MDM2 Degrader-1		Others
	PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].		Others
T12350	P53 and MDM2 proteins-interaction-inhibitor dihydrochloride		Others
	p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is a interaction inhibitor between p53 and MDM2 proteins.		Others
T82179	HOXB7 8–25	MDM2 32-46
	HOXB7 8–25 (MDM2 32-46) is a peptide epitope derived from MDM2 that can induce both antigen-specific and tumor-reactive CD4+ T cell responses [1].
T79483	MDM2/XIAP-IN-3
	MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing cancer cell proliferation and inducing apoptosis [1].
T78699	MDMX/MDM2-IN-2
	MDMX/MDM2-IN-2 is a potent dual inhibitor of p53-MDM2/MDMX, demonstrating dissociation constants (Kis) of 0.23 μM for MDM2 and 2.45 μM for MDMX. It effectively disrupts the interaction between p53 and MDM2 proteins, ther...
T72832	MDM2-p53-IN-16
	MDM2-p53-IN-16 is a potent inhibitor of the MDM2-p53 complex, exhibiting an IC 50 value of 4.3 nM for the dissociation of the human p53/MDM2 complex. It effectively reactivates p53, leading to apoptosis and cell-cycle ar...
T81830	MDM2/XIAP-IN-1
	MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potential applications in cancer research [1].
T79012	MDM2/XIAP-IN-2
	MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP). It promotes the degradation of MDM2 and impedes translation of XIAP mRNA, effectively inhibit...
T74936	MDM2/4-p53-IN-3
	MDM2/4-p53-IN-3, an inhibitor of MDM2/4-p53 protein-protein interactions (PPIs), exhibits potent activity with IC50 values of 18.5 nM for MDM2-p53 and 14.8 nM for MDM4-p53. This compound is applicable in cancer research,...
T74935	MDM2/4-p53-IN-2
	MDM2/4-p53-IN-2 (2q) is a potent dual inhibitor of MDM2/MDM4 and activator of p53, demonstrating IC50 values of 70.7 nM for MDM2-p53 and 81.4 nM for MDM4-p53 complexes. It facilitates cell cycle regulation, promotes apop...
T63438	Rel-MDM2/4-p53-IN-3
	rel-MDM2/4-p53-IN-3 is an MDM2/4-p53 protein-protein interaction (PPI) inhibitor that acts on MDM2-p53 and MDM4-p53 with IC50 values of 18.5 nM and 14.8 nM, respectively. rel-MDM2/4-p53-IN-3 can be used to study cancers,...