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Cat No. | Product Name | Synonyms | Targets |
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T39295 | Remlarsen | MRG-201 | |
Remlarsen (MRG-201), a miR-29b mimic, functions as a miR-29b agonist with the potential to prevent the formation of fibrotic scars or cutaneous fibrosis. | |||
T39294 | Cobomarsen | MRG-106,Cobomarsen | |
Cobomarsen (MRG-106) is an oligonucleotide inhibitor targeting miR-155. This compound effectively suppresses various gene pathways involved in cell survival, such as JAK/STAT, MAPK/ERK, and PI3K/AKT. Cobomarsen is partic... | |||
T12104 | MRGPRX1 agonist 1 | Others | |
MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM). | |||
T63812 | MrgprX2 antagonist-8 | Others | |
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases. | |||
T60466 | MRGPRX1 agonist 2 | ||
MRGPRX1 agonist 2 (compound 1a) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC 50 value of 0.48 μM. MRGPRX1 agonist 2 has the potential to be used in neuropath... | |||
T40271 | MrgprX2 antagonist-3 | MrgprX2 antagonist-3 | |
MrgprX2 antagonist-3 is a potent inhibitor of MrgprX2. It holds promising potential for investigating skin inflammatory disorders. | |||
T40273 | MrgprX2 antagonist-2 | MrgprX2 antagonist-2 | |
MrgprX2 antagonist-2 is a potent antagonist of MrgprX2. It holds potential for investigating skin inflammatory disorders. | |||
T63766 | MrgprX2 antagonist-7 | ||
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation. | |||
T40270 | MrgprX2 antagonist-1 | MrgprX2 antagonist-1 | |
MrgprX2 antagonist-1, is a novel MrgprX2 antagonist compound. It exhibits potential for exploration in studying cutaneous inflammatory disorders. | |||
T40176 | MrgprX2 antagonist-5 | MrgprX2 antagonist-5 | |
MrgprX2 antagonist-5, which acts as a potent antagonist of MrgprX2. It exhibits the ability to effectively inhibit the activity of MrgprX2, making it an ideal candidate for research related to inflammatory skin disorders... | |||
T61332 | MRGPRX4 modulator-1 | ||
MRGPRX4 modulator-1 (compound 31-2) is a potent antagonist of the mas-related g-protein receptor X4 (MRGPR X4) with an IC50 < 100 nM against MRGPR4. It is utilized for the investigation of MRGPR X4 dependent diseases inc... | |||
T61183 | MRGPRX4 modulator-2 | ||
MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune dis... | |||
T60497 | MRGPRX1 agonist 3 | ||
MRGPRX1 agonist 3 (compound 1f) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC50 of 0.22 μM. MRGPRX1 agonist 3 can be used for neuropathic pain research[1]. | |||
T63549 | MRGPRX1 agonist 4 | ||
MRGPRX1 agonist 4 is a potent and orally active Mas-related G protein-coupled receptor X1 (MRGPRX1) positive conformation modulator (EC50: 0.1 μM). MRGPRX1 agonist 4 ameliorated the behavioral thermal allergic response i... | |||
T63394 | MrgprX2 antagonist-6 | ||
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation. | |||
T40268 | MrgprX2 antagonist-4 | MrgprX2 antagonist-4 | |
MrgprX2 antagonist-4 and compound B-51 E117, is a potent MrgprX2 antagonist. It specifically targets and inhibits the MrgprX2 receptor, making it suitable for investigating various inflammatory skin disorders. | |||
T63578 | Mrgx2 antagonist-1 | ||
Mrgx2 antagonist-1 is a potent antagonist of Mrgx2 (Mas-related Gene X2) and can be used to study Mrgx2-mediated diseases and disorders. | |||
T28095 | MrgX1-Activator-1 | ||
MrgX1-Activator-1 is a MrgX1 receptor activator. | |||
T70340 | JHU-58 | ||
JHU-58 is a novel dipeptide MrgC agonist. JHU-58 inhibited both mechanical and heat hypersensitivity in rats after an L5 spinal nerve ligation (SNL). JHU58 attenuated the evoked excitatory postsynaptic currents in subs... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03276 | BLBP Protein, Human, Recombinant | Human | E. coli |
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic l... | |||
TMPJ-00671 | FABP7 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl... | |||
TMPH-01640 | MRGPRX2 Protein, Human, Recombinant (His) | Human | E. coli |
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules ... |