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Search Results for " kir4.1 "

7

Compounds

Cat No. Product Name Synonyms Targets
T8372 VU0134992 VU 0134992 Potassium Channel
VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM
T13316 VU0134992 hydrochloride Potassium Channel
VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 µM).
T73267 VU6036720 Potassium Channel
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probability and single-channel current amplitude.
T6592 ML133 hydrochloride ML133 HCl Potassium Channel
ML133 hydrochloride (ML133 HCl) is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
T13320 VU591 hydrochloride Potassium Channel
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr...
T72295 VU6036720 hydrochloride
VU6036720 hydrochloride is a potent, specific inhibitor of Kir4.1/5.1 channels, demonstrating an IC50 value of 0.24 μM in vitro. It is utilized in the research of brain and kidney functions.
T17240 VU041 Others
VU041 is an inhibitor of Anopheles gambiae and Aedes aegypti inward rectifier potassium 1 channels (IC50: 2.5 μM and 1.7 μM, respectively). VU041 inhibits appreciably is mammalian Kir2.1 (IC50: 12.7 μM) and has less inhi...
TargetMol